SR9009 mapiritsi 100 mapiritsi/bhodhoro

Product Name:SR9009

Spacification: 10 mg / piritsi 100 mapiritsi / bhodhoro

Mutengo:$80/bhodhoro

MOQ: 1 bhodhoro

Lab: LianFu Bio

Produt discription

SR9009, a REV-ERBagonist, inowedzera kudzvinyirirwa kwemajini kunotungamirirwa neREV-ERBα / ERBβ (IC50: 670 / 800 nM).Kuburikidza ne activation yeREV-ERB, SR9009 inogona kuderedza circadian locomotor chiitiko panguva yerima uye kushandura maitiro ekutaura epakati wachi genes mu hypothalami yemakonzo.Iyo circadian pateni yekutaura kweakarongedzerwa emagetsi emagetsi muchiropa, skeletal tsandanyama, uye adipose tissue yakashandurwawo mumakonzo akafumurwa kuSR9009, zvichikonzera kuwedzera kwekushandisa kwesimba.

SR9009 (100 mg/kg, ip, bid, kwemazuva makumi matatu) aigonakuderedza mafuta akawandauye zvinoshamisakuvandudza dyslipidemiauyehyperglycemia.